Lectures

ECMO is an acronym, which stands for Extracorporeal Membrane Oxygenation. It represents a technique, which is able to support patients with refractory respiratory failure or a cardiac failure. In essention it temporarily replaces pulmonary and/or cardiac function. In this webinar we will discuss the different types of ECMO, the HEMS teams, ECMO used in a setting of cardiac resuscitation, VA-ECMO for cardiac failure and precise ECLS.

In bovenstaande Engelstalige video vertelt Dr. Anja Wagner van het Erasmus MC over de samenwerking tussen medisch specialisten, laboratorium specialisten en onderzoeker rond erfelijke en familiaire tumoren. Deze samenwerking is van groot belang voor het voorkomen en behandelen van kanker en andere gezondheidsproblemen bij patiënten met (mogelijk) een erfelijke aanleg voor goed en/of kwaadaardige tumoren.

Hemophilia is a severe bleeding disorder caused by a deficiency of Factor VIII or IX. Patients are treated with intravenously administered coagulation factor concentrate 2-4 times every week to prevent severe and frequent bleeding episodes 
AAV-based gene therapy aims to increase factor levels in order to reduce the risk of bleeding by expression of FVIII and IX in the liver. In the Erasmus MC 6 patients have successfully been treated in the last few years, leading to reduced bleeding without the need of factor concentrates. 
In this webinar we will report the latest results on efficacy, side effects and hurdles of gene therapy. Given the increased number of gene therapy initiatives for other rare diseases, the Erasmus MC should invest in gene therapy in order to cure rare inherited disorders and improve patient outcome and quality of life. 

Presented by: Prof. Dr. John Martens & Dr. Linetta Koppert 

ABC are not just the first letters of the alphabet, in the Erasmus MC ABC represents a Center of excellence for the management of patients with breast cancer. To this end we perform clinical, translational and fundamental research and teach the next generation allowing us to provide optimal care. 

Presented by: Prof. Harry de Koning

The Department of Public Health (ACE Screening & Prevention) is excited to announce the initiation of the first large-scale European multi-centered implementation of volume CT LUNG CANCER SCREENING in the Netherlands and 4 other European countries (through an 8 million EU HORIZON2020 Grant 4-IN-THE-LUNG-RUN of which professor Harry de Koning is the principal investigator). 

The trial’s main goal is to assess the relative safety of a personalized risk-based screening interval based on the result of the first baseline test result(s), but will during implementation investigate the effectiveness of tailored recruitment strategies, methods to integrate co-morbidity reducing strategies, and innovative methods like AI and biomarkers. It plans to initially enroll 26,000 high risk individuals. 

Presented by: Dr. Marlies Wakkee

In this lecture dr. Marlies Wakkee, dermatologist and associate professor at the Erasmus MC Cancer Institute, describes how care, research and teaching at the ACE Skin Cancer are set out from a broad perspective. This ranges from feeling responsible for organising optimal care for all skin cancer patients in the Netherlands to investigating advanced skin cancer by innovative, translational research lines and collaborating with external partners like the Erasmus School of Health Policy and Management and TU Delft within the Convergence and various public private partnerships. 

Presented by: Prof Liesbeth van Rossum and Prof Erica van den Akker

Obesity is a complex disease. This webinar brings you up to date on novel strategies in diagnostics for underlying causes of obesity as well as innovative and personalized treatments for obesity in children and adults.

Presented by: Prof. dr. John Martens

Sustainable health care heavily relies on powerful biomarkers. The ACE InnovaBIM (Innovative Biomarkers In Medicine) aims to develop tissue- and bodyfluid-derived biomarkers. Implementation of beyond state-of-the-art biomarkers developed within our ACE.

Presented by: Dr. Judith Cuypers

In this presentation, by Judith Cuypers, various aspects of care for congenital heart disease patients will be discussed, and information about the contemporary care for these patients will be given. This information is made possible by the ACE for Congenital Cardiology. Watch to learn more about the provided and improving care for congenital heart disease patients.

Presented by: Dr. Julie Nonnekens and Dr. Laura Mezzanotte

Our mission is to directly and non-invasively visualize and quantify structure and function within living cells and organisms to reveal molecular mechanisms of disease, enhance our understanding of disease processes, which will allow us to develop new diagnostics and therapeutics in a wide range of clinical applications. In this presentation by Dr. Julie Nonnekens and Dr. Laura Mezzanotte we will give examples of imaging of subcellular processes such as DNA damage induction by targeted radionuclide therapy and imaging of molecular events using bioluminescence in cells, whole organs and small animals.

Presented by: Prof. Jan Hoeijmakers

Aging is associated with onset of numerous diseases severely affecting quality of life. Studying very rare premature aging DNA repair syndromes in children we found that DNA damage is a major cause of systemic aging and that nutritional interventions keep unexpected promises to promote healthy aging.  

Dr. Birgit Koch, Dr. Sinno Simons and Laura Peeters, PhD Candidate

In this lecture womb to grave pharmacology is discussed. Amongst all pharmacokinetics, pharmacodynamics, therapeutic drug monitoring and toxicology in research, education and clinical setting are introduced in this lecture. Current pharmacotherapy is most often based on one dose fits all strategy. In our ACE our focus is to individualize pharmacotherapy and to optimize dosing, moving towards a ‘one dose fits one’ strategy. 

Presented by: dr. Wendy van de Sande 

In this lecture we will learn about the neglected tropical disease mycetoma for which currently the only option is to remove the infected lesions surgically or to amputate the infected limb. Characteristic of this disease is that the micro-organisms causing this infection build a protective structure called a grain inside the infected tissue. We will take the audience along our journey to find clues how this structure is formed. How we try to use this information to design drugs which are effective against mycetoma and how we have involved an open source drug discovery project in order to solve these issues.

Presented by: Dr. B. Groot Koerkamp

Bas Groot Koerkamp is a surgical oncologist and transplant surgeon in the ACE Hepato-Pancreato-Biliary Diseases. In this ACE lecture on regional chemotherapy for liver tumors, he explains the challenges of introducing an old treatment for colorectal liver metastases and intrahepatic cholangiocarcinoma.

Presented by: prof. dr. Wiro Niessen & dr. Harro Seelaar

This ACE lecture traces the path of an artificial intelligence radiology application that was originally developed within Erasmus MC as academic tool, but has now found its way to daily clinical practice, enabling individual patient decision-making in dementia and related brain abnormalities.